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Article

Early interferon therapy for hepatitis C virus infection rescues polyfunctional, long-lived CD8+ memory T cells.

Journal of virology - 1 Oct 2008

Badr Gamal, Bédard Nathalie, Abdel-Hakeem Mohamed S, Trautmann Lydie, Willems Bernard, Villeneuve Jean-Pierre, Haddad Elias K, Sékaly Rafick P, Bruneau Julie, Shoukry Naglaa H

Abstract excerpt

The majority of acute hepatitis C virus (HCV) infections progress to chronicity and progressive liver damage. Alpha interferon (IFN-alpha) antiviral therapy achieves the highest rate of success when IFN-alpha is administered early during the acute phase, but the underlying mechanisms are unknown....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18667516
DOI: 10.1128/JVI.01083-08
PMCID: PMC2566289

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18667516-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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