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Transactivation of human endogenous retroviruses by tumor viruses and their functions in virus-associated malignancies

14 Jan 2019

Abstract excerpt

Human endogenous retroviruses (HERVs), viral-associated sequences, are normal components of the human genome and account for 8-9% of our genome. These original provirus sequences can be transactivated to produce functional products. Several reactivated HERVs have been implicated in cancers and autoimmune diseases. An emerging body of literature supports a potential role of reactivated HERVs in viral diseases, in...

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PMID: 30643113
DOI: 10.1038/s41389-018-0114-y

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