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RNA helicases, DDX5 and DDX17, facilitate lytic reactivation of gammaherpesviruses

21 Apr 2025

Abstract excerpt

Human gammaherpesviruses comprise of Kaposi's sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV), and are oncogenic viruses that cause life-long infections. The gammaherpesviruses utilize an extensive virus-host interaction network for facilitating viral replication, whereby virus-encoded proteins modulate host processes. Thus, identifying targets of viral proteins that aid in gammaherpesviral...

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PMID: 40257982
DOI: 10.1371/journal.ppat.1013009

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