Group 2 Innate Lymphoid Cells Express Functional NKp30 Receptor Inducing Type 2 Cytokine Production

Abstract excerpt

Group 2 innate lymphoid cells (ILC2) are important in effector functions for eliciting allergic inflammation, parasite defense, epithelial repair, and lipid homeostasis. ILC2 lack rearranged Ag-specific receptors, and although many soluble factors such as cytokines and lipid mediators can influence ILC2, direct interaction of these cells with the microenvironment and other cells has been less explored. Natural...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Eosinophilic Esophagitis
• Share to IL-33, ST2, and ILC Pathways
• Share to Immune Cell Function and Interaction