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Article

Apolipoprotein E ϵ4 is positively related to spatial performance but unrelated to hippocampal volume in healthy young adults.

Behavioural brain research - 15 Feb 2016

Stening Eva, Persson Jonas, Eriksson Elias, Wahlund Lars-Olof, Zetterberg Henrik, Söderlund Hedvig

Abstract excerpt

The apolipoprotein E (APOE) ϵ4 allele is known to be a major genetic risk factor for Alzheimer's disease (AD). It has been linked to especially episodic memory decline and hippocampal atrophy in both healthy and demented elderly populations. In young adults, ϵ4 carriers have shown better performance in episodic memory compared to non-carriers. Spatial memory, however, has not been thoroughly assessed in relation...

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Source

Identifiers

PMID: 26581118
DOI: 10.1016/j.bbr.2015.11.006

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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