Article
ABCG2 in peptic ulcer: gene expression and mutation analysis.
Journal of applied genetics - 1 Aug 2016
Salagacka-Kubiak Aleksandra, Żebrowska Marta, Wosiak Agnieszka, Balcerczak Mariusz, Mirowski Marek, Balcerczak Ewa
Abstract excerpt
The aim of this study was to evaluate the participation of polymorphism at position C421A and mRNA expression of the ABCG2 gene in the development of peptic ulcers, which is a very common and severe disease. ABCG2, encoded by the ABCG2 gene, has been found inter alia in the gastrointestinal tract, where it plays a protective role eliminating xenobiotics from cells into the extracellular environment. The materials...
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