Article
Association of SLCO1B1 1b with peptic ulcer amongst Japanese patients taking low-dose aspirin.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Mar 2012
Shiotani Akiko, Murao Takahisa, Sakakibara Takashi, Tarumi Ken-Ichi, Manabe Noriaki, Kamada Tomoari, Kusunoki Hiroaki, Haruma Ken
Abstract excerpt
BACKGROUND: In the recent case-control study, we showed an inverse association between peptic ulcer and angiotensin type 1 receptor (AT1R) blockers (ARBs) or HMG-Co A reductase inhibitors (statins). The aim was to evaluate whether the genotypes of uptake and efflux transporters of ARBs and statins relate to the presence of peptic ulcer and/or ulcer bleeding associated with aspirin use. METHODS: Patients taking...
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