Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

C3435T polymorphism of the ABCB1 gene: impact on genetic susceptibility to peptic ulcers.

Pharmacological reports : PR - 1 Jan 2011

Sałagacka Aleksandra, Bartczak Malwina, Zebrowska Marta, Jażdżyk Marcin, Balcerczak Mariusz, Janiuk Robert, Mirowski Marek, Balcerczak Ewa

Abstract excerpt

The functional single nucleotide polymorphism (SNP) C3435T in exon 26 of the ABCB1 gene encoding the xenobiotic transporter P-glycoprotein (P-gp) may influence susceptibility to several diseases, as well as the clinical outcome of treatment with P-gp substrates. Exposure to environmental chemicals is thought to be involved in peptic ulcer pathogenesis and then later in stomach cancer development. About 80% of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to ATP Binding Cassette Transporter, Subfamily B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Share to Helicobacter Infections

Share to Helicobacter pylori

Share to Peptic Ulcer

Share to Prevalence

Share to Sex Factors

Source

Identifiers

PMID: 22001987
DOI: 10.1016/s1734-1140(11)70615-6

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

C3435T polymorphism of the ABCB1 gene: impact on genetic susceptibility to peptic ulcers.PMID 22001987Read ↗

Investigation of ABCB1 1236 and 2677 SNPs in patients with peptic ulcer.Semantic proximity Read ↗

Polymorphism at position T-129C in the promoter region of ABCB1 gene in peptic ulcer patients: a case control studySemantic proximity Read ↗

Lack of association of the MDR1 C3435T polymorphism with susceptibility to gastric cancer and peptic ulcer: a systemic review and meta-analysis.Semantic proximity Read ↗

MDR1 C3435T polymorphism has no influence on developing Helicobacter pylori infection-related gastric cancer and peptic ulcer in Japanese.Semantic proximity Read ↗

ABCG2 in peptic ulcer: gene expression and mutation analysis.Semantic proximity Read ↗

C3435T Polymorphism of the ABCB1 Gene in Polish Patients with Inflammatory Bowel Disease: A Case-Control and Meta-Analysis Study.Semantic proximity Read ↗

Is the ABCB1 gene associated with the increased risk of gastric cancer development?--preliminary research.Semantic proximity Read ↗

Association between ABCB1 (3435C>T) polymorphism and susceptibility of colorectal cancer: A meta-analysis.Semantic proximity Read ↗

P-glycoprotein expression in Helicobacter pylori-positive patients: the influence of MDR1 C3435T polymorphism.Semantic proximity Read ↗

Association between the C3435T single-nucleotide polymorphism of multidrug resistance 1 gene and risk of gastric cancer.Semantic proximity Read ↗

Genetic polymorphism of ABCB1 gene (C3435T) in patients with inflammatory bowel diseases. Is there any gender dependency?Semantic proximity Read ↗

The Association between ABCB1 C1236T/C3435T SNPs and H. pylori Infection among Jordanians.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.