Article
Justification of Genetic Factors for Predicting the Risk of Acute Bleeding in Peptic Ulcer Disease.
Journal of medicine and life - 1 Jan 2000
Grynchuk Fedir Vasilyevich, Dutka Ivan Ivanovich, Panchuk Iryna Ihorivna, Volkov Roman Anatolyevich, Sheremet Michael Ivanovich, Maksymyuk Vitaliy Vasilyevich, Tarabanchuk Volodymyr Volodymyrovich, Bilyk Ihor Ivanovich, Myshkovskii Yuriy Mykolayovych
Abstract excerpt
PAI genotyping for the G43A and 4G/5G polymorphisms was performed in 60 patients with peptic ulcer disease: 12 with an uncomplicated ulcer, 5 with perforation, the rest with ongoing bleeding. Fourteen patients had recurrent bleeding. The 5G/5G and G43A genotypes were not detected in patients with uncomplicated ulcers. All patients with ulcer perforation had the G43G genotype, 60% of patients had the 4G/4G...
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