Article
Glucose starvation induces mutation and lineage-dependent adaptive responses in a large collection of cancer cell lines.
International journal of oncology - 1 Jan 2016
He Ningning, Kim Nayoung, Jeong Euna, Lu Yiling, Mills Gordon B, Yoon Sukjoon
Abstract excerpt
Tolerance of glucose deprivation is an important factor for cancer proliferation, survival, migration and progression. To systematically understand adaptive responses under glucose starvation in cancers, we analyzed reverse phase protein array (RPPA) data of 115 protein antibodies across a panel of approximately 170 heterogeneous cancer cell lines, cultured under normal and low glucose conditions. In general,...
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