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Article

Targeting molecular addictions in cancer.

British journal of cancer - 25 Nov 2014

Vivanco I

Abstract excerpt

Cancer cells depend on a finite number of critical signals for their survival. Oncogene addiction, that is, the acquired dependence of a cancer cell on the activity of a single oncogenic gene product, has been the basis for the targeted therapy paradigm, and operationally defines such signals. Additionally, cancer cells have altered metabolic requirements that create addictions to specific nutrients such as...

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Identifiers

PMID: 25268375
DOI: 10.1038/bjc.2014.461
PMCID: PMC4260023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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