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Article

The polymorphism in miR-25 attenuated the oncogenic function in gastric cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Apr 2016

Zhou Jianping, Zhou Jiangang, Wang Weimin, Li Weiling, Wu Lulu, Li Gang, Shi Jun, Zhou Sujun

Abstract excerpt

miR-25 was identified as an essential oncogene by promoting the growth and metastasis through TOB1 in gastric cancer (GC). The function of the single nucleotide polymorphism (SNP) located in the mature region of miR-25 (rs41274221) has not been investigated. In this study, we aimed to explore the involvement of rs41274221 in miR-25 in gastric cancer. We found that SNP rs41274221 in miR-25 was participated in the...

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Share to Carcinogenesis
Share to Cell Proliferation
Share to Gene Expression Regulation, Neoplastic
Share to Intracellular Signaling Peptides and Proteins
Share to MicroRNAs
Share to Neoplasm Metastasis
Share to Stomach Neoplasms
Share to Tumor Suppressor Proteins

Source

Identifiers

PMID: 26572149
DOI: 10.1007/s13277-015-4376-0

Genes

TOB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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