Article
The Functional Variant in the 3'UTR of IGF1 with the Risk of Gastric Cancer in a Chinese Population.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2015
Jiang Haiqiang, Wang Huiyun, Ge Fengyuan, Wu Lamei, Wang Xiao, Chen Shengxia
Abstract excerpt
BACKGROUND/AIMS: IGF-1 can act as an endocrine hormone and its signaling server as essential roles in regulating tumorigenesis. Polymorphisms in IGF-1 have been reported associated bad prognosis of with human cancer, but their association with the risk of human gastric cancer (GC) has not been found so far. In this study rs6218 located in the 3'UTR of IGF-1 was selected to evaluate its relationship with the risk...
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