Article
Evaluation of a novel functional single-nucleotide polymorphism (rs35010275 G>C) in MIR196A2 promoter region as a risk factor of gastric cancer in a Chinese population.
Medicine - 1 Nov 2014
Xu Ming, Qiang Fulin, Gao Yan, Kang Meiyun, Wang Meilin, Tao Guoquan, Gong Weida, Zhu Haixia, Wu Dongmei, Zhang Zhengdong, Zhao Qinghong
Abstract excerpt
Single-nucleotide polymorphisms (SNPs) in microRNAs (miRNAs) have been suggested to influence the occurrence and progression of cancer through altering the expression and biological function of miRNAs. The aim of this study was to investigate whether the potential functional SNPs in MIR196A2 promoter had effect on the susceptibility to gastric cancer (GC) in a Chinese population.We conducted a 2-stage...
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