Article
Function analysis of rs9589207 polymorphism in miR-92a in gastric cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Apr 2016
Liu Changming, Zhang Ying, Chen Haijun, Jiang Lixing, Xiao Daping
Abstract excerpt
MiR-92a was identified as an essential oncogene by promoting the cell proliferation through FBXW7 in gastric cancer (GC). The function of the single nucleotide polymorphism (SNP) located in the mature region of miR-92a (rs9589207) has not been investigated. We found that rs9589207 in miR-92a was involved in the occurrence of GC by acting as a tumor protective factor and was highly associated with tumor size in GC...
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