Article
Polymorphism rs1057147 located in mesothelin gene predicts lymph node metastasis in patients with gastric cancer.
Applied microbiology and biotechnology - 1 Jun 2023
Shen Kuan, Cheng Quan, Xiao Jian, Zhou Xinyi, Wang Yuanhang, Liu Kanghui, Ni Peidong, Fan Hao, Hu Li, Xu Zekuan, Yang Li
Abstract excerpt
Lymph node metastasis, a crucial factor in the spread of gastric cancer (GC), is strongly associated with a negative prognosis for patients. This study aimed to investigate the association of the mesothelin (MSLN) gene polymorphisms (rs3764247, rs3764246, rs12597489, rs1057147, and rs3765319) with the risk of lymph node metastasis of GC patients in a Chinese Han population. The PCR-LDR genotyping was used to...
