Article
MICB typing by PCR amplification with sequence specific primers.
Immunogenetics - 1 Mar 2003
González Segundo, Rodríguez-Rodero Sandra, Martínez-Borra Jesús, López-Vázquez Antonio, Rodrigo Luis, López-Larrea Carlos
Abstract excerpt
MICB is a member of the MIC (MHC class I chain-related gene) family. Sixteen MICB alleles have been described; however, the functional relevance and population distribution of MICB alleles or their potential association to disease has not yet been evaluated. In this study, we have developed a PCR system using sequence-specific primers (PCR-SSP) that allows unambiguous amplification of all MICB alleles. This...
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