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Article

TAOK3, a novel genome-wide association study locus associated with morphine requirement and postoperative pain in a retrospective pediatric day surgery population.

Pain - 1 Sept 2014

Cook-Sather Scott D, Li Jin, Goebel Theodora K, Sussman Emily M, Rehman Mohamed A, Hakonarson Hakon

Abstract excerpt

Candidate gene studies have revealed limited genetic bases for opioid analgesic response variability. Genome-wide association studies facilitate impartial queries of common genetic variants, allowing identification of novel genetic contributions to drug effect. Illumina (Illumina Inc, San Diego, CA, USA) single nucleotide polymorphism (SNP) arrays were used to investigate SNP associations with total morphine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24909733
DOI: 10.1016/j.pain.2014.05.032
PMCID: PMC4157963

Genes

TAOK3

Provenance

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