Article
Vascular Proteomics Reveal Novel Proteins Involved in SMC Phenotypic Change: OLR1 as a SMC Receptor Regulating Proliferation and Inflammatory Response.
PloS one - 1 Jan 2015
Kang Dong Hoon, Choi Mina, Chang Soyoung, Lee Min Young, Lee Doo Jae, Choi Kyungsun, Park Junseong, Han Eun Chun, Hwang Daehee, Kwon Kihwan, Jo Hanjoong, Choi Chulhee, Kang Sang Won
Abstract excerpt
Neointimal hyperplasia of vascular smooth muscle cells (VSMC) plays a critical role in atherosclerotic plaque formation and in-stent restenosis, but the underlying mechanisms are still incompletely understood. We performed a proteomics study to identify novel signaling molecules organizing the VSMC hyperplasia. The differential proteomics analysis in a balloon-induced injury model of rat carotid artery revealed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
