Association study of apolipoprotein E promoter polymorphism (-427 T/C) and Alzheimer's disease in a Tunisian population.

doi:10.1016/j.neurol.2015.10.001

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Article

Association study of apolipoprotein E promoter polymorphism (-427 T/C) and Alzheimer's disease in a Tunisian population.

Revue neurologique - 1 Feb 2016

Achouri-Rassas A, Ben Ali N, Fray S, Kechaou M, Oudiaa Zakraoui N, Hadj-Fredj S, Cherif A, Anane N, Echebi S, Messaoud T, Belal S

Abstract excerpt

BACKGROUND: Alzheimer's disease (AD) is a progressive neurodegenerative disorder with an as yet poorly understood etiology. Both environmental and genetic factors have been implicated as predisposing factors. The apolipoprotein E (APOE) ɛ4 allele is an established genetic susceptibility factor for AD for several populations including the Tunisian population. Polymorphism rs769446 (-427 T/C) at the promoter region...

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PMID: 26563666
DOI: 10.1016/j.neurol.2015.10.001

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APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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