Article
Common variants in LEPR, IL6, AMD1, and NAMPT do not associate with risk of juvenile and childhood obesity in Danes: a case-control study.
BMC medical genetics - 11 Nov 2015
Hollensted Mette, Ahluwalia Tarunveer S, Have Christian Theil, Grarup Niels, Fonvig Cilius Esmann, Nielsen Tenna Ruest Haarmark, Trier Cæcilie, Paternoster Lavinia, Pedersen Oluf, Holm Jens-Christian, Sørensen Thorkild I A, Hansen Torben
Abstract excerpt
BACKGROUND: Childhood obesity is a highly heritable disorder, for which the underlying genetic architecture is largely unknown. Four common variants involved in inflammatory-adipokine triggering (IL6 rs2069845, LEPR rs1137100, NAMPT rs3801266, and AMD1 rs2796749) have recently been associated with obesity and related traits in Indian children. The current study aimed to examine the effect of these variants on...
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