Article
Variants near MC4R are associated with obesity and influence obesity-related quantitative traits in a population of middle-aged people: studies of 14,940 Danes.
Diabetes - 1 Mar 2009
Zobel Dorit P, Andreasen Camilla H, Grarup Niels, Eiberg Hans, Sørensen Thorkild I A, Sandbaek Annelli, Lauritzen Torsten, Borch-Johnsen Knut, Jørgensen Torben, Pedersen Oluf, Hansen Torben
Abstract excerpt
OBJECTIVE: Variants downstream of the melanocortin-4 receptor gene (MC4R) have been reported to associate with obesity. We examined rs17782313, rs17700633, rs12970134, rs477181, rs502933, and near MC4R for association with obesity-related quantitative traits, obesity, and type 2 diabetes in Danish individuals. RESEARCH DESIGN AND METHODS: The variants were investigated for association with...
