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Article

Evaluation of common genetic variants identified by GWAS for early onset and morbid obesity in population-based samples.

International journal of obesity (2005) - 1 Feb 2013

den Hoed M, Luan J, Langenberg C, Cooper C, Sayer A A, Jameson K, Kumari M, Kivimaki M, Hingorani A D, Grøntved A, Khaw K-T, Ekelund U, Wareham N J, Loos R J F

Abstract excerpt

BACKGROUND: Meta-analysis of case-control genome-wide association studies (GWAS) for early onset and morbid obesity identified four variants in/near the PRL, PTER, MAF and NPC1 genes. OBJECTIVE: We aimed to validate association of these variants with obesity-related traits in population-based samples. DESIGN: Genotypes and anthropometric traits were available in up to 31 083 adults from the Fenland, EPIC-Norfolk,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22430306
DOI: 10.1038/ijo.2012.34
PMCID: PMC3680864

Genes

MAF
NPC1
PRL
PTER

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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