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Article

Clinicopathologic and Genomic Analysis of TP53-Mutated Endometrial Carcinomas.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 May 2021

Momeni-Boroujeni Amir, Dahoud Wissam, Vanderbilt Chad M, Chiang Sarah, Murali Rajmohan, Rios-Doria Eric V, Alektiar Kaled M, Aghajanian Carol, Abu-Rustum Nadeem R, Ladanyi Marc, Ellenson Lora H, Weigelt Britta, Soslow Robert A

Abstract excerpt

PURPOSE: Copy number-high endometrial carcinomas were described by The Cancer Genome Atlas as high-grade endometrioid and serous cancers showing frequent copy-number alterations (CNA), low mutational burden (i.e., non-hypermutant), near-universal TP53 mutation, and unfavorable clinical outcomes. We sought to investigate and compare the clinicopathologic and molecular characteristics of non-hypermutant...

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Identifiers

PMID: 33602681
DOI: 10.1158/1078-0432.CCR-20-4436
PMCID: PMC8530276

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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