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Article

Correlative Assessment of p53 Immunostaining Patterns and TP53 Mutation Status by Next-Generation Sequencing in High-Grade Endometrial Carcinomas.

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Nov 2023

Matsumoto Nana, Manrai Padmini, Rottmann Douglas, Wu Xinyu, Assem Hisham, Hui Pei, Buza Natalia

Abstract excerpt

TP53 mutations are frequently identified in the copy number-high molecular subgroup of endometrial carcinomas (ECs). P53 immunohistochemistry (IHC) is a widely used surrogate marker reflecting the mutational status of TP53 , and recent reports have shown ~95% concordance between the two methods in ECs. While these results are promising, studies evaluating the correlation between different p53 IHC staining...

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Identifiers

PMID: 36730675
DOI: 10.1097/PGP.0000000000000930

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Correlative Assessment of p53 Immunostaining Patterns and TP53 Mutation Status by Next-Generation Sequencing in High-Grade Endometrial Carcinomas.PMID 36730675Read ↗

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