Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prevalence of pain-related single nucleotide polymorphisms in patients of African origin with sickle cell disease.

Pharmacogenomics - 1 Nov 2015

Jhun Ellie H, Yao Yingwei, He Ying, Mack A Kyle, Wilkie Diana J, Molokie Robert E, Wang Zaijie Jim

Abstract excerpt

BACKGROUND: Prospective pain genetics research is hindered by a lack of data on the prevalence of polymorphisms in pain-relevant genes for patients with sickle cell disease (SCD). For African-Americans in general, limited information is available in public databases. METHODS: We prioritized and examined the genotype and allele frequencies of 115 SNPs from 49 candidate pain genes in 199 adult African-Americans and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Anemia, Sickle Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Black or African American

Share to Gene Frequency

Share to Prevalence

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 26555434
DOI: 10.2217/pgs.15.126
PMCID: PMC4909047

Genes

SCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prevalence of pain-related single nucleotide polymorphisms in patients of African origin with sickle cell disease.PMID 26555434Read ↗

Evaluating Associations between Average Pain Intensity and Genetic Variation in People with Sickle Cell Disease: An Exploratory Study.Semantic proximity Read ↗

S100B single nucleotide polymorphisms exhibit sex-specific associations with chronic pain in sickle cell disease in a largely African-American cohort.Semantic proximity Read ↗

Genetic variants of GCH1 associate with chronic and acute crisis pain in African Americans with sickle cell disease.Semantic proximity Read ↗

An Expert Review of Pharmacogenomics of Sickle Cell Disease Therapeutics: Not Yet Ready for Global Precision MedicineSemantic proximity Read ↗

Can heterogeneity of chronic sickle-cell disease pain be explained by genomics? A literature review.Semantic proximity Read ↗

Clinical and genetic factors are associated with pain and hospitalisation rates in sickle cell anaemia in Cameroon.Semantic proximity Read ↗

Vasopressin SNP pain factors and stress in sickle cell disease.Semantic proximity Read ↗

Pharmacogenetics of Pain Management in Zimbabwean Patients With Sickle Cell DiseaseSemantic proximity Read ↗

IL1A rs1800587 associates with chronic noncrisis pain in sickle cell disease.Semantic proximity Read ↗

A polygenic score for acute vaso-occlusive pain in pediatric sickle cell disease.Semantic proximity Read ↗

Transient receptor potential polymorphism and haplotype associate with crisis pain in sickle cell disease.Semantic proximity Read ↗

The AVPR1A Gene and Its Single Nucleotide Polymorphism rs10877969: A Literature Review of Associations with Health Conditions and Pain.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.