New genetic regulators question relevance of abundant yolk protein production in C. elegans.

doi:10.1038/srep16381

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Article

New genetic regulators question relevance of abundant yolk protein production in C. elegans.

Scientific reports - 10 Nov 2015

Van Rompay Liesbeth, Borghgraef Charline, Beets Isabel, Caers Jelle, Temmerman Liesbet

Abstract excerpt

Vitellogenesis or maternal yolk formation is considered critical to the reproduction of egg-laying animals. In invertebrates, however, most of its regulatory genes are still unknown. Via a combined mapping and whole-genome sequencing strategy, we performed a forward genetic screen to isolate novel regulators of yolk production in the nematode model system Caenorhabditis elegans. In addition to isolating new...

Topics

Alleles
Animals
Animals, Genetically Modified
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Chromosome Mapping
Egg Proteins
Gene Expression
Genes, Reporter
Mutation
RNA, Messenger
Reproduction
Transcription, Genetic

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Identifiers

PMID: 26553710
DOI: 10.1038/srep16381
PMCID: PMC4639837

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