Article
Susceptibility of monocytes to activation correlates with atherogenic mitochondrial DNA mutations.
Experimental and molecular pathology - 1 Dec 2015
Orekhov A N, Zhelankin A V, Kolmychkova K I, Mitrofanov K Yu, Kubekina M V, Ivanova E A, Sobenin I A
Abstract excerpt
We have recently evaluated the susceptibility of circulating monocytes to pro- and anti-inflammatory activation comparing samples from healthy individuals and patients with asymptomatic carotid atherosclerosis. Surprisingly, we found a dramatic individual difference in susceptibility to activation between monocytes isolated from the blood of different subjects, regardless of the presence or absence of...
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