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Article

Characterization of inherited scavenger receptor overexpression and abnormal macrophage phenotype in a normolipidemic subject with planar xanthomas.

Journal of lipid research - 1 Jul 1996

Giry C, Giroux L M, Roy M, Davignon J, Minnich A

Abstract excerpt

It is proposed that, in hyperlipidemia, foam cells develop in cutaneous xanthomas from the uptake by the macrophage scavenger receptor (SR) of low density lipoproteins (LDL) that are modified due to increased residence time in plasma. We have observed extensive xanthelasmas and planar xanthomas in the absence of hyperlipidemia in two siblings. In blood monocytes from one sibling, 125I-labeled acetylated LDL...

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PMID: 8827515

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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