Article
Association of ACE, VEGF and CCL2 gene polymorphisms with Henoch-Schönlein purpura and an evaluation of the possible interaction effects of these loci in HSP patients.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University - 1 Jul 2017
Mohammadian Tahereh, Bonyadi Mortaza, Nabat Elahe, Rafeey Mandana
Abstract excerpt
BACKGROUND: Henoch-Schönlein purpura (HSP) is a multisystem, small vessel, leucocytoclastic vasculitis. It is predominantly a childhood vasculitis, rarely reported in adults. Studies have shown that several different genetic factors such as genes involved in inflammatory system and renin-angiotensin system (RAS) are important in the pathogenesis of Henoch-Schönlein purpura. OBJECTIVES: The purpose of this study...
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