Article
Chemokine MCP1/CCL2 gene polymorphism influences Henoch-Schönlein purpura susceptibility in Iranian Azeri-Turkish patients.
International journal of dermatology - 1 Nov 2015
Bonyadi Mortaza, Mohammadian Tahereh, Rafeey Mandana, Sadeghi Shabestri Mahnaz, Mortazavi Fakhrossadat, Aliyari Behzad
Abstract excerpt
BACKGROUND: Henoch-Schönlein purpura (HSP) is the most common small-vessel vasculitis and mainly affects children. Although its pathophysiology is unknown, several studies have indicated the possible involvement of infections and genetic factors in the development of HSP. The human leukocyte antigen (HLA) gene family and several other genes involved in the inflammatory system have been studied. The CCL2 gene,...
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