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Article

CHFR hypermethylation, a frequent event in acute myeloid leukemia, is independently associated with an adverse outcome.

Genes, chromosomes & cancer - 1 Feb 2016

Gao Li, Liu Fang, Zhang Hui, Sun Junzhong, Ma Yigai

Abstract excerpt

The CpG island of the promoter region of the checkpoint with fork-head associated and ring finger gene (CHFR), a mitotic checkpoint gene with tumor-suppressor functions, is hypermethylated in various human cancers. The objective of this study was to evaluate the frequency of aberrant CHFR promoter methylation in acute myeloid leukemia (AML) patients in an attempt to improve prognostication. CHFR promoter...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26542416
DOI: 10.1002/gcc.22322

Genes

CHFR
SRSF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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CHFR hypermethylation, a frequent event in acute myeloid leukemia, is independently associated with an adverse outcome.PMID 26542416Read ↗

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