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Article

Aberrant methylation of the CHFR gene in advanced hepatocellular carcinoma.

Hepato-gastroenterology - 1 Jan 2000

Sakai Mitsuru, Hibi Kenji, Kanazumi Naohito, Nomoto Shuji, Inoue Soichiro, Takeda Shin, Nakao Akimasa

Abstract excerpt

BACKGROUND/AIMS: Recently, aberrant methylation of the CHFR gene associated with gene silencing has been reported in several cancers. We examined the methylation status of the CHFR gene in primary hepatocellular carcinomas (HCCs) and evaluated the correlation between the methylation status and the malignancy of HCC. METHODOLOGY: We first examined the methylation status of the CHFR promoter region and mRNA...

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Identifiers

PMID: 16334792

Genes

CHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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