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Article

Non-syndromic cleft palate: Association analysis on three gene polymorphisms of the folate pathway in Asian and Italian populations.

International journal of immunopathology and pharmacology - 1 Jan 2000

Carinci Francesco, Palmieri Annalisa, Scapoli Luca, Cura Francesca, Borelli Francesco, Morselli Paolo Giovanni, Nouri Nayereh, Abdali Hossein, Gianni Aldo Bruno, Russillo Antonio, Docimo Raffaella, Martinelli Marcella

Abstract excerpt

Periconceptional folic acid supplementation can reduce the risk of inborn malformations, including orofacial clefts. Polymorphisms of MTHFR, TCN2, and CBS folate-related genes seem to modulate the risk of cleft lip with or without cleft palate (CL/P) in some populations. CL/P and cleft palate only (CPO) are different malformations that share several features and possibly etiological causes. In the present...

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Identifiers

PMID: 31663447
DOI: 10.1177/2058738419858572
PMCID: PMC6822179

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Non-syndromic cleft palate: Association analysis on three gene polymorphisms of the folate pathway in Asian and Italian populations.PMID 31663447Read ↗

Non-syndromic cleft lip with or without cleft palate in Asian populations: Association analysis on three gene polymorphisms of the folate pathway.Semantic proximity Read ↗

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SNPs in folate pathway are associated with the risk of nonsyndromic cleft lip with or without cleft palate, a meta-analysis.Semantic proximity Read ↗

Two SNPs rs1801133 and rs1801394 in folate pathway are associated with the risk of nonsyndromic cleft lip with or without cleft palateSemantic proximity Read ↗

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