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Article

Diversification of the Primary Antibody Repertoire by AID-Mediated Gene Conversion.

Results and problems in cell differentiation - 1 Jan 2015

Lanning Dennis K, Knight Katherine L

Abstract excerpt

Gene conversion, mediated by activation-induced cytidine deaminase (AID), has been found to contribute to generation of the primary antibody repertoire in several vertebrate species. Generation of the primary antibody repertoire by gene conversion of immunoglobulin (Ig) genes occurs primarily in gut-associated lymphoid tissues (GALT) and is best described in chicken and rabbit. Here, we discuss current knowledge...

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Source

Identifiers

PMID: 26537386
DOI: 10.1007/978-3-319-20819-0_12

Genes

GALT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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