Article
Immune-mediated Skin Inflammation is Similar in Severe Atopic Dermatitis Patients With or Without Filaggrin Mutation.
Acta dermato-venereologica - 15 Jun 2016
Dajnoki Zsolt, Béke Gabriella, Mócsai Gábor, Kapitány Anikó, Gáspár Krisztián, Hajdu Krisztina, Emri Gabriella, Nagy Bence, Kovács Ilona, Beke Lívia, Dezső Balázs, Szegedi Andrea
Abstract excerpt
Inflammatory cytokines can impair the skin barrier, but the question as to whether barrier alterations affect keratinocyte immune responses remains unanswered. The aim of this study was to investigate whether immune-mediated skin inflammation differs between severe atopic dermatitis patients with or without filaggrin mutation. The levels of filaggrin, inflammatory T helper 2 polarizing cytokines (thymic stromal...
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