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Article

The atopic march: current insights into skin barrier dysfunction and epithelial cell-derived cytokines.

Immunological reviews - 1 Jul 2017

Han Hongwei, Roan Florence, Ziegler Steven F

Abstract excerpt

Atopic dermatitis often precedes the development of other atopic diseases. The atopic march describes this temporal relationship in the natural history of atopic diseases. Although the pathophysiological mechanisms that underlie this relationship are poorly understood, epidemiological and genetic data have suggested that the skin might be an important route of sensitization to allergens. Animal models have begun...

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Identifiers

PMID: 28658558
DOI: 10.1111/imr.12546
PMCID: PMC5492959

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