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Article

The role of filaggrin loss-of-function mutations in atopic dermatitis.

Current opinion in allergy and clinical immunology - 1 Oct 2008

O'Regan Grainne M, Irvine Alan D

Abstract excerpt

PURPOSE OF REVIEW: To provide a comprehensive summary of recent genetic advances as they relate to the pathogenesis of atopic dermatitis. RECENT FINDINGS: Atopic dermatitis is a common inflammatory skin disease with a complex cause, resulting from an elaborate interplay between environmental, immunological and genetic factors. The disease is often the prelude to an atopic diathesis that includes asthma and other...

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Identifiers

PMID: 18769192
DOI: 10.1097/ACI.0b013e32830e6fb2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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