Article
Prevalence of POMC R236G mutation in Pakistan.
Obesity research & clinical practice - 1 Sept 2016
Shabana, Hasnain Shahida
Abstract excerpt
Obesity has become a great health issue and socioeconomic burden globally in the past few decades and has afflicted Pakistan in the same way. However, there is limited research on obesity genetics in Pakistan. Proopiomelanocortin (POMC) neurons bear leptin receptor and act as anorectic targets of leptin in the brain. Leptin binding induces a series of processing events producing melanocortins which then bind to...
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