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Leptin deficiency and leptin gene mutations in obese children from Pakistan.

International journal of pediatric obesity : IJPO : an official journal of the International Association for the Study of Obesity - 1 Oct 2011

Fatima Warda, Shahid Adeela, Imran Muhammad, Manzoor Jaida, Hasnain Shahida, Rana Sobia, Mahmood Saqib

Abstract excerpt

BACKGROUND: Congenital leptin deficiency is a rare human genetic condition clinically characterized by hyperphagia and acute weight gain usually during the first postnatal year. The worldwide data on this disorder includes only 14 cases and four pathogenic mutations have been reported in the leptin gene. STUDY OBJECTIVE: The objectives of this study were to measure serum leptin levels in obese children and to...

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PMID: 21854111
DOI: 10.3109/17477166.2011.608431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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