Article
Effect of CYP2C19 Polymorphisms on the Platelet Response to Clopidogrel and Influence on the Effect of High Versus Standard Dose Clopidogrel in Carotid Artery Stenting.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery - 1 Feb 2016
González A, Moniche F, Cayuela A, García-Lozano J R, Torrecillas F, Escudero-Martínez I, Gonzalez-Marcos J R, Mayol A, Montaner J
Abstract excerpt
OBJECTIVES: Genetic background has been identified to be a major predictor of post-clopidogrel platelet inhibition in patients undergoing coronary stenting. However, there is a lack of data on clopidogrel response regarding genotype in patients undergoing carotid artery stenting (CAS). The influence of the most common allelic variants of CYP2C19 phenotypes and genotypes on response to baseline clopidogrel and on...
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