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Article

A candidate-gene association study of topiramate-induced weight loss in obese patients with and without type 2 diabetes mellitus.

Pharmacogenetics and genomics - 1 Feb 2016

Li Qingqin S, Lenhard James M, Zhan Yiping, Konvicka Karel, Athanasiou Maria C, Strauss Richard S, Francke Stephan

Abstract excerpt

OBJECTIVE: Clinical response to topiramate can vary greatly in obese patients. Identifying genetic variants associated with treatment response could help gain insight into the mechanism of action of topiramate. Little is known about the relationship between genetic variability and topiramate treatment response. We performed a large-scale candidate-gene study to identify genetic risk factors predictive of...

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Source

Identifiers

PMID: 26524290
DOI: 10.1097/FPC.0000000000000185

Genes

INSR
GRIA3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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