Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of the HTR2C gene and antipsychotic induced weight gain: a meta-analysis.

The international journal of neuropsychopharmacology - 1 Oct 2007

De Luca Vincenzo, Mueller Daniel J, de Bartolomeis Andrea, Kennedy James L

Abstract excerpt

The 5-HT2C receptor has been hypothesized to represent an important modulator in feeding behaviour. Evidence was based on the observation that knock-out mice for the 5-HT2C receptor gene (HTR2C) develop obesity and that many atypical antipsychotics with potent 5-HT2C antagonism may induce weight gain in susceptible individuals. Pharmacogenetic studies focusing mainly on the -759C/T promoter polymorphism...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antipsychotic Agents
Share to Body Mass Index

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Databases, Bibliographic

Share to Gene Frequency

Share to Pharmacogenetics

Share to Racial Groups

Share to Receptor, Serotonin, 5-HT2C

Share to Weight Gain

Source

Identifiers

PMID: 17291373
DOI: 10.1017/S1461145707007547

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of the HTR2C gene and antipsychotic induced weight gain: a meta-analysis.PMID 17291373Read ↗

Role of 5-HT2C receptor gene variants in antipsychotic-induced weight gainSemantic proximity Read ↗

Polymorphisms of the HTR2C gene and antipsychotic-induced weight gain: an update and meta-analysis.Semantic proximity Read ↗

Weight gain with antipsychotic drugs: the role of the 5-HT2C receptor (HTR2C) and other genes.Semantic proximity Read ↗

HTR2C haplotypes and antipsychotics‐induced weight gain: X‐linked multimarker analysisSemantic proximity Read ↗

Genetics of antipsychotic-induced weight gain: update and current perspectives.Semantic proximity Read ↗

Association of antipsychotic drug-induced weight gain with a 5-HT2C receptor gene polymorphism.Semantic proximity Read ↗

-759C>T Polymorphism of the HTR2C Gene is Associated with Second Generation Antipsychotic-Induced Weight Gain in Female Patients with Schizophrenia.Semantic proximity Read ↗

Association of HTR2C, but not LEP or INSIG2, genes with antipsychotic-induced weight gain in a German sample.Semantic proximity Read ↗

A meta-analysis of potential genetic factors associated with antipsychotic-induced weight gain in adults with severe mental illness.Semantic proximity Read ↗

-759 C/T polymorphism of 5-HT2C receptor gene and early phase weight gain associated with antipsychotic drug treatment.Semantic proximity Read ↗

Clozapine-induced weight gain associated with the 5HT2C receptor -759C/T polymorphism.Semantic proximity Read ↗

Antipsychotic induced weight gain: genetics, epigenetics, and biomarkers reviewed.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.