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Article

INSIG2 rs7566605 single nucleotide variant and global DNA methylation index levels are associated with weight loss in a personalized weight reduction program.

Molecular medicine reports - 1 Jan 2018

Pirini Francesca, Rodriguez-Torres Sebastian, Ayandibu Bola Grace, Orera-Clemente María, Gonzalez-de la Vega Alberto, Lawson Fahcina, Thorpe Roland J, Sidransky David, Guerrero-Preston Rafael

Abstract excerpt

Single nucleotide polymorphisms associated with lipid metabolism and energy balance are implicated in the weight loss response caused by nutritional interventions. Diet‑induced weight loss is also associated with differential global DNA methylation. DNA methylation has been proposed as a predictive biomarker for weight loss response. Personalized biomarkers for successful weight loss may inform clinical decisions...

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Share to DNA Methylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29138870
DOI: 10.3892/mmr.2017.8039
PMCID: PMC5780113

Genes

INSIG2

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