Article
[Establishment of Integration-Free Human Induced Pluripotent Stem Cells from A Patient with Primary Myelofibrosis].
Zhongguo shi yan xue ye xue za zhi - 1 Oct 2015
Xu Jing, Sheng Meng-Yao, Zhou Yuan, Xing Wen, Bai Jie, Wen Wei, Ji Guang-Zhen, Zhang Hong-Yan, Jin Hui, Lyu Cui-Cui, Yuan Wei-Ping, Zhang Xiao-Bing, Cheng Tao
Abstract excerpt
OBJECTIVE: To establish the primary myelofibrosis (PMF)-induced pluripotent stem cell line (iPSC) by means of iPSC techinique so as to provide a experimental model for studying the blood disease mechanisms. METHODS: Induced pluripotent stem cells were generated from mononuclear cells isolated from a PMF patient with JAK2(V617F) mutation by using episomal vectors. RESULTS: PMF-derived iPSC was established from the...
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