Article
Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders.
Blood - 24 Dec 2009
Ye Zhaohui, Zhan Huichun, Mali Prashant, Dowey Sarah, Williams Donna M, Jang Yoon-Young, Dang Chi V, Spivak Jerry L, Moliterno Alison R, Cheng Linzhao
Abstract excerpt
Human induced pluripotent stem (iPS) cells derived from somatic cells hold promise to develop novel patient-specific cell therapies and research models for inherited and acquired diseases. We and others previously reprogrammed human adherent cells, such as postnatal fibroblasts to iPS cells, which resemble adherent embryonic stem cells. Here we report derivation of iPS cells from postnatal human blood cells and...
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