Article

Development of a Stable Human iPSC Line from Peripheral Blood: A Control Resource for Disease Modeling

2025-08-21

Abstract excerpt

<h4>Introduction</h4> Traditional disease modeling approaches have primarily utilized animal models and immortalized cell lines to investigate disease mechanisms and develop therapeutic strategies. However, previous research indicates that only about 5% of therapeutic interventions tested in animal models eventually receive regulatory approval for human use, highlighting limitations. The discovery of human-induce...

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Literature Corpus work: 8302eabb-c2bc-57c7-a284-74831fc65e01
DOI: 10.1101/2025.08.21.671443

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