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Modeling blood diseases with human induced pluripotent stem cells

1 Jun 2019

Abstract excerpt

Induced pluripotent stem cells (iPSCs) are derived from somatic cells through a reprogramming process, which converts them to a pluripotent state, akin to that of embryonic stem cells. Over the past decade, iPSC models have found increasing applications in the study of human diseases, with blood disorders featuring prominently. Here, we discuss methodological aspects pertaining to iPSC generation, hematopoietic...

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PMID: 31171568
DOI: 10.1242/dmm.039321

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