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Generation of iPSC lines from peripheral blood mononuclear cells from 5 healthy adults

27 Dec 2018

Abstract excerpt

We describe the generation and characterization of 5 human induced pluripotent stem cell (iPSC) lines derived from peripheral blood mononuclear cells (PBMCs) of healthy adult individuals. The PBMCs were reprogrammed using non-integrating Sendai viruses containing the reprogramming factors POU5F1 (OCT4), SOX2, KLF4 and MYC. The iPSC lines exhibited a normal karyotype, expressed pluripotency markers and...

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PMID: 30605840
DOI: 10.1016/j.scr.2018.101380

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