Article
[Isocitrate dehydrogenase gene mutations in acute myeloid leukemia].
Zhongguo shi yan xue ye xue za zhi - 1 Aug 2011
Zhou Xiao-Juan, Zhang Su-Jiang, Qiao Chun, Shen Yun-Feng, Li Jian-Yong
Abstract excerpt
The purpose of this study was to identify point mutation of the isocitrate dehydrogenase gene (IDH1 and IDH2) in patients with acute myeloid leukemia(AML) and its clinical significance. 90 de novo AML patients were selected for this study, the genomic DNA was served as template, the exon4 of IDH1 and IDH2 were amplified respectively. The IDH mutation was detected by using directly sequencing method for PCR...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
